PRION-SEEDING ACTIVITY IS WIDELY DISTRIBUTED IN TISSUES OF SPORADIC CREUTZFELDT-JAKOB DISEASE PATIENTS

Human prion diseases are neurodegenerative disorders caused by abnormally folded prion proteins in the central nervous system.These proteins can be detected using the quaking-induced conversion assay.Compared with other bioassays, this assay is extremely sensitive and was used in the present study to determine GSPOT prion distribution in sporadic C

The use of psychostimulants and alcohol NIKE AIR MAX 90 disrupts blood-brain barrier (BBB) integrity, resulting in alterations to cellular function, and contributes to neurotoxicity.The BBB is the critical boundary of the central nervous system (CNS) where it maintains intracellular homeostasis and facilitates communication with the peripheral circ